ABSTRACT
<p><b>OBJECTIVE</b>To explore the mechanism of EA in treatment of acute pancreatitis.</p><p><b>METHODS</b>Twenty-four healthy male Wistar rats were randomly divided into 3 groups, a control group, a model group and an EA group. In the model group, rat acute pancreatitis model was prearpared by intraperitoneal injection of Caerulein, and in the EA group, EA was given at "Zusanli" (ST 36) and "Tianshu" (ST 25) of the model rat. The gastric emptying rate, small intestinal impelling ratio, myeloperoxidase activity in the pancreas tissue, pathological score of the pancreas and serum amylase were detected.</p><p><b>RESULTS</b>Compared with the control group, both the gastric emptying rate and the intestinal impelling ratio significantly decreased in the model group (P<0.05), and they significantly increased in the EA group compared with the model group (P<0.05). Myeloperoxidase activity in the pancreas tissue, pathological score of the pancreas and serum amylase activity significantly decreased in the EA group as compared with the model group (P<0.05).</p><p><b>CONCLUSION</b>EA can significantly improve the disturbance of gastrointestinal motility induced by acute pancreatitis and relieve pathological damage of pancreas.</p>
Subject(s)
Animals , Male , Rats , Acute Disease , Amylases , Blood , Electroacupuncture , Gastrointestinal Motility , Pancreas , Pathology , Pancreatitis , Therapeutics , Peroxidase , Metabolism , Rats, WistarABSTRACT
<p><b>OBJECTIVE</b>To introduce Back-propagation (BP) neural network and genetic algorithm for multi-objective optimization of extraction technology of Cortex Fraxini.</p><p><b>METHOD</b>BP neural network was established and optimized with uniform design. Genetic algotithm was used for multi-objective optimization of extraction technology of cortex fraxini.</p><p><b>RESULT</b>the optimization of extraction was as follows: extraction temperature was 99 degrees C, concentration of EtOH was 50%, liquid-solid ratio was 7, extraction time was 94 min. The proportional error between predictive value and practical measured value was just -1.16% and -5.14%.</p><p><b>CONCLUSION</b>Back-propagation neural network and genetic algorithm for multi-objective optimization of extraction technology of cortex fraxini is advisable.</p>
Subject(s)
Algorithms , Drugs, Chinese Herbal , Chemistry , Neural Networks, ComputerABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of infrasonic field of minesweeper on psychology of minesweeper crews.</p><p><b>METHODS</b>An experimental ship was selected to conduct infrasonic minesweeping, a control ship of the same type was selected to operate likewise with the infrasound generator turned off, and another group of coast-servicemen was chosen as blank control. Attention-span test, digit memory test, two-digital numbers list and profile of mood states (POMS) were used to test the ship crews and coast-servicemen.</p><p><b>RESULTS</b>There were no significant differences in psychological parameters between the two ship crews before the experiment. But the scores of two-digit figures list in ship crews were significant lower than that in coast-servicemen, (31.2 +/- 11.8, 36.4 +/- 14.5 respectively vs 45.8 +/- 13.9, P < 0.05). POMS showed that the scores of anger-hostility, fatigue-inertia, and confusion-bewilderment in both ship crew groups [(15.5 +/- 6.4, 18.3 +/- 6.8), (12.1 +/- 5.0,12.3 +/- 4.9), (11.6 +/- 4.4, 12.5 +/- 4.8), respectively] were higher than those in coast-servicemen (13.9 +/- 7.0, 7.6 +/- 4.1, 8.2 +/- 4.3, respectively, P < 0.05 or 0.01), while vigor-activity in experimental group (15.0 +/- 5.9) was lower than that in coast-servicemen (19.7 +/- 4.7). After the experiment, the scores of experimental crews in digit memory test (14.5 +/- 5.0), vigor-activity (12.2 +/- 5.8), fatigue-inertia (15.8 +/- 6.2) were significantly different from those of control crews (17.3 +/- 4.8, 16.5 +/- 4.6, 11.3 +/- 5.1).</p><p><b>CONCLUSIONS</b>The infrasonic field from minesweeper may injure the crew's psychological health and some neurobehavioral function.</p>